| Genomic rearrangements in OPA1 gene frequent in adOA
| Patients with autosomal dominant optic atrophy show aberrations on MLPA testing
| | Ophthalmology Times | Multiplex ligation probe amplification (MLPA), a relatively new technique for detecting copy number variations in genomic sequences, has been used to study the pathomechanism of autosomal dominant optic neuropathy. |
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| Supranuclear gaze disturbances can be confusing
| Here's what the general ophthalmologist needs to know
| | Ophthalmology Times | | Supranuclear gaze palsy should be suspected in patients with bilateral and symmetric vertical or horizontal gaze difficulty. Use of specific maneuvers to bypass the supranuclear input to the ocular motor nuclei can help to establish a supranuclear localization to the problem and direct neuroimaging to the supranuclear pathways in the brain and brainstem. |
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| Optic neuropathy may be drug-related, physician says
| Condition awareness an important factor for adequate patient counseling
| | Ophthalmology Times | | Ophthalmologists need to warn patients that the use of a phophodiesterase-5 inhibitor may increase the risk of the development of ischemic optic neuropathy. |
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